Introduction To Zerodol-SP Tablet
Zerodol-SP Tablet treats pain, inflammation and fever. This medicine can be prescribed for conditions such as osteoarthritis, rheumatoid arthritis, fibromyalgia, ankylosing spondylitis, etc. It is a combination of aceclofenac, paracetamol and serratiopeptidase. They work by blocking the pain signals and reducing the inflammation in the affected area. Thus it relieves symptoms such as headache, muscle pain, joint pain, toothache, nerve pain, etc.
Zerodol-SP Tablet should be taken as prescribed by your physician. The dose of the medication will be adjusted depending on the severity of your clinical symptoms. Take them after food to avoid stomach discomfort. Try not to chew or break the tablet; swallow it as a whole.
Side effects of Zerodol-SP Tablet include stomach pain, heartburn, drowsiness, loss of appetite, nausea, diarrhoea and vomiting. These adverse effects usually go away on their own and should not be of any concern. Contact your doctor If they persist or become worse.
Zerodol-SP Tablet may be contraindicated (unsafe) for people with stomach ulcers, liver and kidney diseases, blood clotting disorders, ischaemic heart disease, ulcerative colitis, Crohn's disease and allergies to aceclofenac, paracetamol and serratiopeptidase. Always let your doctor know of any health conditions you might have. This combination drug is generally considered safe for most people.
Uses of Zerodol-SP Tablet
Zerodol-SP Tablet is used to treat inflammation, fever and mild to moderate pain. This medicine can be prescribed for conditions including:
- Rheumatoid arthritis
- Dysmenorrhea (menstrual pain)
- Neuralgia or neuritis (inflammation and damage of nerves)
- Low back pain
- Post-operative and post-traumatic pain
- Fibromyalgia (musculoskeletal pain)
- Ankylosing spondylitis (fusing of vertebrae bones)
Zerodol-SP Tablet contains aceclofenac, paracetamol and serratiopeptidase. It blocks the pain signals and reduces the inflammation in the affected area. Thus, it relieves a wide array of symptoms such as headache, muscle pain, joint pain, ear pain, toothache, nerve pain, etc.
This medicine may be prescribed to people experiencing any kind of moderate to severe pain or swelling in the body. It acts fast and provides quick pain relief to the user for a significant period. Make sure to follow your doctor's prescription for the best results.
Side effects of Zerodol-SP Tablet
Zerodol-SP Tablet does not come with significant side effects that require medical attention and usually go away on their own. If the problems persist or get worse, please get in touch with your doctor.
Common side effects of Zerodol-SP Tablet include:
- Stomach pain
- Loss of appetite
Although rare, you might be hypersensitive to the content of this medication. Visit the nearest hospital and seek medical attention immediately if you experience severe side effects of Zerodol-SP Tablet, including:
- Yellowing of the skin and eyes
- Dark-coloured urine
- Pale stools
- Allergic skin rash with itching
- Swelling of face, throat and limbs
- Breathing difficulty
- Severe abdominal pain
- High Fever
- Changes in heart rate
How Zerodol-SP Tablet works
Zerodol-SP Tablet contains aceclofenac, paracetamol and serratiopeptidase. It works by inhibiting pain signals in the brain and certain chemicals in our body that induce inflammation, swelling, fever and pain. It also breaks down specific proteins at the site of inflammation, which results in a speedy recovery of the tissue.
Aceclofenac is a non-selective non-steroidal anti-inflammatory drug (NSAID) and phenylacetic acid derivative. As an NSAID, it reduces pain and inflammation without the harmful side effects of steroids. This potent anti-inflammatory medicine works by inhibiting enzymes called COX-1 and COX-2. This lowers the synthesis of prostaglandins (hormone-like chemicals responsible for pain and inflammation).
Paracetamol, also known as acetaminophen, is a non-narcotic (non-habit forming) analgesic-antipyretic agent (reduces both pain and fever). It has fewer side effects than its more potent counterpart, aceclofenac, partly because it isn’t an effective anti-inflammatory agent.
Serratiopeptidase (aka serralysin, serrapeptidase or serrapeptase) is a proteolytic enzyme made by the bacteria Enterobacterium Serratia found inside silkworms. Certain literature claims that this enzyme helps break down proteins to reduce inflammation and pain in conditions like arthritis, osteoporosis, fibromyalgia and headache. There isn’t more information regarding this enzyme's efficacy and side effects.
Always take Zerodol-SP Tablet medicine as prescribed by your physician. Don't exceed the recommended dosage. Take this tablet as a whole with ample water; do not chew or crush it. You may take it with your meals to reduce side effects like stomach discomfort and nausea.
If you forget to take this medication, take it as soon as you remember. If it is time for your next dose, ignore the one you missed and continue with the next. To compensate for a missed dose, avoid taking twice the amount.
Taking more than the prescribed dose of Zerodol-SP Tablet over a long period may lead to overdose and intoxication. If you experience signs like a change in the urine colour or severe abdominal pain, contact your doctor or visit the nearest hospital immediately.
Zerodol-SP Tablet may be contraindicated for people with stomach ulcers, liver and kidney diseases, blood clotting problems, ulcerative colitis, Crohn's disease and allergies to aceclofenac, paracetamol or serratiopeptidase. Always let your doctor know of any health conditions you might have. Generally, this medicine is considered safe for most people.
Do note that Serrapeptase might delay blood clotting. Therefore, it is not recommended to take this medicine along with other drugs that affect blood clotting, such as warfarin, enoxaparin, naproxen, etc.
Can I take Zerodol-SP Tablet if I’m pregnant?
Zerodol-SP Tablet should be used during pregnancy only if the benefits justify the potential risk. Consult your doctor and adjust your dosage if necessary.
Can I take Zerodol-SP Tablet if I’m breastfeeding?
The active ingredients of Zerodol-SP Tablet might pass into the breastmilk but in negligible amounts. Consult your doctor before taking this medication.
Is drinking alcohol while taking Zerodol-SP Tablet safe?
It is recommended not to consume alcohol while taking Zerodol-SP Tablet because the side effects, such as dizziness, may worsen. Please consult your doctor.
Can I drive after taking Zerodol-SP Tablet?
It is not recommended to take it before driving since Zerodol-SP Tablet causes dizziness as its common adverse effect that might impact your driving ability.
Can I take Zerodol-SP Tablet if I have/had kidney diseases?
Individuals who have a history of kidney disease or are currently experiencing renal impairment are advised to exercise caution when consuming this medication. Let your doctor know so they may change the prescription.
Can I take Zerodol-SP Tablet if I have/had liver diseases?
Individuals with a history or present diagnosis of liver disease are advised to exercise caution when consuming this medication. Let your doctor know so they may change the prescription.
It is recommended to avoid or decrease the consumption of alcohol, coffee, tea and other caffeinated drinks while taking Zerodol-SP Tablet.
Zerodol-SP Tablet might be contraindicated (unsafe) for people with stomach ulcers, liver and kidney diseases, blood clotting problems, ulcerative colitis, ischaemic heart disease, Crohn's disease and allergies to aceclofenac, paracetamol or serratiopeptidase.
Consult your doctor if you are currently taking the following medicines: Antiepileptics (phenytoin, carbamazepine), pain medications (tramadol, aspirin, naproxen, ibuprofen, hydrocodone, oxycodone, ketorolac, prilocaine), anti-hypertensive drugs (lisinopril, hydrochlorothiazide), anticoagulants (warfarin, apixaban, rivaroxaban) and antidepressants (duloxetine, escitalopram).
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Frequently Asked Questions
Q. What is Zerodol-SP Tablet’s content?
Zerodol-SP Tablet contains three ingredients: aceclofenac, paracetamol and serratiopeptidase. It works by blocking the pain signals and reducing inflammation in the body.
Q. Can the use of Zerodol-SP Tablet cause dizziness?
Zerodol-SP Tablet can cause dizziness as a side effect. Lay down and rest. Avoid the next dose and contact your doctor if it persists for too long.
Q. Can I stop taking Zerodol-SP Tablet when my pain is relieved?
It is perfectly safe to stop using Zerodol-SP Tablet once the pain is gone. In case of severe injury or disorder, it's better to stop the medication when your doctor advises.
Q: What are the side effects of Zerodol-SP Tablet tablet?
Zerodol-SP Tablet may produce side effects like stomach pain, heartburn, nausea, indigestion, diarrhoea and vomiting. Contact your doctor if they persist or get worse.
Q. What is the use of Zerodol-SP Tablet?
Zerodol-SP Tablet is used to treat pain, inflammation and fever. It relieves symptoms such as headache, muscle pain, joint pain, toothache, nerve pain, etc.
Q. Is Zerodol-SP Tablet a strong painkiller?
Yes, Zerodol-SP Tablet is a strong painkiller that can treat mild to moderate pain associated with various conditions, including arthritis, migraines and neuritis.
Aceclofenac and gastric ulcers
Aceclofenac, one of the three ingredients in Zerodol-SP Tablet, is a COX-1 and COX-2 inhibitor. In gastric mucosa, COX-1 is responsible for synthesising PGE2 and PGI2, which is responsible for increasing bicarbonate and mucus secretion, maintaining adequate blood flow to the mucosa and reducing gastric acid and pepsin secretion.
Since aceclofenac inhibits COX-1 or Cyclooxygenase-1, it adversely affects the health of the stomach lining and causes gastrointestinal ulceration.
That is why the dose of Zerodol-SP Tablet is adjusted for patients with pre-existing gastric ulcers. An overdose for a prolonged period causes gastric ulcers in patients with a perfectly healthy stomach lining.